The Ticking Clock: Understanding Fertility and Age
For couples trying to conceive, age often becomes a silent but powerful factor. It influences everything from natural conception to assisted reproductive techniques like IUI (Intrauterine Insemination). While IUI is one of the least invasive and most affordable fertility treatments, its effectiveness can vary significantly depending on the woman’s age.
At Dr. Richa Gangwar’s fertility clinic in Lucknow, many hopeful couples walk in wondering, “Is IUI the right option for us — and do we still have time?” This article answers those questions with clarity, compassion, and facts.
What Is IUI?
IUI (Intrauterine Insemination) is a procedure where washed, concentrated sperm is placed directly into the uterus during ovulation, increasing the chances of fertilization.
It is often recommended for:
- Mild male factor infertility
- Unexplained infertility
- Ovulation issues
- Cervical mucus problems
It’s less invasive than IVF and can be combined with ovulation induction medications for better timing.
Why Age Plays a Key Role in IUI Success
Age affects fertility in both men and women, but in women, the decline is more noticeable and biologically time-sensitive. This is due to two main reasons:
1. Ovarian Reserve Declines with Age
Women are born with all the eggs they’ll ever have. As age increases:
- The number of eggs decreases
- The quality of eggs also declines
- Risk of chromosomal abnormalities increases
This affects the chances of successful fertilization — even when using assisted methods like IUI.
2. Hormonal Changes Affect Ovulation
After 35, hormonal changes may:
- Shorten or lengthen menstrual cycles
- Cause irregular ovulation
- Lead to poor response to ovulation medications
This makes timing the IUI cycle more challenging.
IUI Success Rates by Age: What Research Shows
While success rates vary case by case, here is a general overview:
- Under 30 years: Success rates can be 18–20% per cycle
- Ages 30–34: Around 15–18% per cycle
- Ages 35–37: Drop to 10–12% per cycle
- Ages 38–40: About 7–9% per cycle
- Over 40 years: Less than 5% per cycle
For women over 35, especially those trying for over a year, timely medical evaluation is essential. IUI can still work — but should not be delayed indefinitely.
Should You Still Try IUI After 35?
Absolutely — but with proper guidance. At Dr. Richa Gangwar’s clinic, we assess:
- Ovarian reserve (using AMH, FSH, and ultrasound)
- Partner’s sperm quality
- Hormonal profile and cycle regularity
- Any history of miscarriage or past treatments
If IUI is suitable, we time the cycle precisely, sometimes use ovulation trigger injections, and monitor closely for best chances. We usually recommend trying up to 3 IUI cycles before exploring IVF if needed.
Other Factors That Affect IUI Success Besides Age
- Uterine health (polyps, fibroids, endometrial lining)
- Tubal patency (IUI won’t work if tubes are blocked)
- Thyroid or insulin resistance (especially in PCOD cases)
- Lifestyle habits (smoking, alcohol, sleep, weight)
- Stress levels — mental wellbeing matters!
Fertility is not just about age — it’s also about overall reproductive health. That’s why our clinic focuses on complete wellness before and during treatment.
How to Improve Your IUI Success — at Any Age
At Dr. Richa Gangwar’s clinic, we guide couples through:
- Personalized cycle tracking
- Ovulation support with mild medication
- Pre-IUI endometrial preparation
- Nutrition and lifestyle changes
- Stress management and emotional support
Even if age is not on your side, science and support can be.
When to Consider Moving from IUI to IVF
IUI may not be ideal if:
- You’re over 37 with low AMH or poor egg quality
- You’ve had 3–4 failed IUI cycles
- There are moderate to severe sperm issues
- Time is a critical factor due to age or medical history
In such cases, IVF or ICSI may offer better success rates, especially when paired with embryo freezing or PGT (genetic testing).
Final Thoughts: Your Fertility Journey Is Unique
Age matters, but it’s not the only deciding factor. With the right guidance, support, and timing, IUI can still be a valuable option — even for women in their mid to late 30s.
At Dr. Richa Gangwar’s fertility clinic in Lucknow, we help couples understand their fertility window and make informed decisions without pressure. Whether you’re just starting out or have tried before, we’re here to help you take the next step with confidence and care.
